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At the protein level, FOXO4-DRI apparently reduced markers tied to myofibroblasts and matrix deposition, including -SMA and Col1a1
However, there were no significant differences between two groups ( P = 0.69)
doi: 10.1016/j.biopha.2023.115521 64 LfflerJNoomAEllinghausADieneltAKempaSDudaGN
Current research presents a complex picture that requires careful interpretation, as studies have yielded mixed results depending on the specific agent studied, patient population, duration of treatment, and methodology employed
Martinez FJ, de Andrade JA, Anstrom KJ, et al
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