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Since levothyroxine requires an acidic gastric environment for optimal dissolution and absorption, and its absorption can be affected by the rate of gastric emptying, patients may experience variations in thyroid hormone levels when starting semaglutide therapy

2015 Apr 30;9:2485-99

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It plays a critical role in converting the food we eat into usable energy, repairing damaged DNA, and activating longevity-related proteins called sirtuins