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This said, stimulants may still be a reasonable first therapeutic choice for previously untreated children with ASD and uncomplicated ADHD

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For patients weighing 150 kg (330 pounds) or more, healthcare providers increase the dose to 1 gram to ensure adequate blood concentrations above the bacterial minimum inhibitory concentration for approximately 50 hours. This ceftriaxone monotherapy approach emerged after mounting azithromycin resistance prompted CDC to abandon dual-drug therapy in 2020, leaving gonorrhea treatment dependent on essentially one antibiotic classa precarious situation as resistance continues evolving globally

Qian F, Mathias N, Moench P, Chi C, Desikan S, Hussain M, et al