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PMC 6461196
Association between use of dipeptidyl peptidase-4 inhibitors and the risk of acute kidney injury: a nested case-control study
During that time period, prescriptions for drugs like Ozempic and Wegovy (semaglutide) increased from about 0.8 million to more than 1.5 million, growing annually at a rate of 5.3%
Signal detection based on PT levels In the Preferred Term (PT) level analysis, we implemented a rigorous screening protocol to exclude conditions that might represent therapeutic indications for GLP-1 receptor agonists and metformin combination therapy, as well as events clearly unrelated to pharmacologically-induced adverse reactions
A pooled analysis of 5 randomized placebo-controlled trials demonstrated a significant 13% reduction in the risk of total stroke with GLP-1 RAs compared with placebo, without significant heterogeneity between trials
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