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The accumulated data support a multifactorial explanation: cardiometabolic burden is reduced, while the rapid separation of MACE event curves in placebo-controlled trials within months and before substantial weight loss together with imaging evidence for plaque stabilization and reduced coronary inflammation, plausibly support a contribution from direct vascular anti-inflammatory and endothelial mechanisms [9], [24], [25]

Thymosin-beta4 has a role in tissue repair and has been found to play an important role in protection, regeneration, and remodeling of injured or damaged tissues

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Sanyal, D., & Raychaudhuri, M