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The foundational target for modern weight loss medications including Semaglutide, Tirzepatide, and Retatrutide
For context, NICE guidance on obesity pharmacotherapy including TA875 (semaglutide for weight management) and TA924 (tirzepatide for managing overweight and obesity) provides a useful framework for understanding how future agents might be positioned in the UK
Consider what happened to Mikhail, a Russian-born American struggling with obesity who had been prescribed tirzepatide, the active ingredient in Mounjaro
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