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La Asociacin Americana de Diabetes (ADA) recomienda un enfoque centrado en el paciente para la seleccin de tratamientos, y en personas con enfermedad cardiovascular aterosclertica, alto riesgo cardiovascular, enfermedad renal crnica o insuficiencia cardaca, un GLP-1 con beneficio cardiovascular demostrado puede considerarse independientemente del uso de metformina
While in many mammalian species UA is further degraded to allantoin, in humans and certain other primates the uricase activity responsible for this metabolic removal has been lost
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Kochan, D
doi: 10.1016/j.ajog.2020.08.103 53 KupermanAAZimmermanAHamadiaSZivOGurevichVFichtmanBet al
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