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Abstract Purpose: A systematic review and meta-analysis was conducted to synthesize the available data from clinical trials and assess the safety issues of tirzepatide (pancreatitis and gallbladder or biliary disease) in type 2 diabetes (T2D) and obesity
For patients with Cushing's syndrome (cortisol excess), NICE recommends specialist endocrinology referral for comprehensive investigation and management
Neither is FDA-approved yet, but both could reshape the competitive pricing picture within the next two to three years
Although early post-marketing surveillance raised concerns about mood changes and suicidal thoughts, subsequent pooled analyses and regulatory reviews have largely been inconclusive
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