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Mechanistic case, trial data, and the open question

stable enough to be ingested as a pill

They are often sufficient for correcting mild dietary deficiencies (e.g., in vegans who dont consume fortified foods) and can sometimes be used for maintaining levels after an initial course of injections, provided absorption is adequately monitored by a healthcare professional

In contrast, consuming too much calcium can prevent the body from absorbing enough magnesium

The zero withdrawal rate in AOD-9604 trials suggests excellent practical tolerability that extends beyond merely counting adverse events to assessing their real impact on treatment continuation