In summary, we have strong converging evidence of reduced alcohol use in individuals taking Semaglutide or Tirzepatide
Indeed, we and others have shown direct protective effects of mesenchymal (bone marrow or adipose derived) stem cells in mutant SOD1 transgenic mouse models of ALS 31,32
FDA-approved oral semaglutide The FDA has approved oral semaglutide (Rybelsus) for type 2 diabetes, and in early 2026, oral semaglutide received FDA approval for weight loss as well
They compared 175 health outcomes between veterans who took GLP-1RA drugs to treat their diabetes and those who took more traditional medications sold under brand names such as Jardiance, Glipizide, and Januvia
Similar content being viewed by others Log in or create a free account to read this content Gain free access to this article, as well as selected content from this journal and more on nature.com or Abbreviations HCC: hepatocellular carcinoma CAH: chronic active hepatitis STAT: signal transducer and activator of transcription Grb-2: growth factor receptor-bound protein 2 ERK: extracellular signal-regulated kinase NF-B: nuclear factor B TNF: tumor necrosis factor MAPK: mitogen activated protein kinase JNK: c- jun N-terminal kinase NF-AT: nuclear factor of activated T cells References Brchot C (1997) Hepatitis C virus 1b, cirrhosis, and hepatocellular carcinoma