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[17] [18] Glibenclamide may occasionally be considered under specialist supervision when other options are unsuitable, with careful monitoring of the infant for signs of hypoglycaemia (poor feeding, jitteriness, unusual sleepiness)

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Conversely, another possibility is that a lower C4B copy number might protect the stability of the host microbiome to some extent by reducing the excessive clearance of beneficial microbes mediated by C4B

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