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Effect of diet on liver glutathione and glutathione reductase [PMID: 5671673] Laboratory literature summary: Effect of diet on liver glutathione and glutathione reductase

However, that doesnt mean that too much methylene blue cant make you sick

Phosphate binders vary somewhat as to the effectiveness at binding phosphate in the intestinal tract and not uncommonly cause such mild gastrointestinal distress as anorexia, nausea, diarrhea, or constipation which may reduce compliance (86)