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ETC abnormalities lead to significant loss of mitochondrial bioenergetic function and oxidative stress, increasing neurons susceptibility to excitotoxic damage, leading to PD (46)

What exists is a growing body of preclinical data, early-phase human research, and a developing clinical consensus among peptide-prescribing physicians that points toward a relatively narrow therapeutic window

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doi:10.1007/s00011-010-0213-8 Arul V, Kartha R, Jayakumar R

Age, genetic disorders, medical conditions, and diet are all factors that can increase the need for certain nutrients