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The development of advanced neuroimaging techniques, particularly positron emission tomography (PET) using radioligands for the translocator protein (TSPO), has enabled the visualization and confirmation of microglial activation in living PD patients [462, 463]

Most people tolerate it well, but mild skin irritation is normal

Risk is almost always a product of self-sourcing unregulated vials , poor reconstitution , non-sterile technique , or wrong dose for goal - all of which we see in patients who come to us after online DIY protocols

Its been shown to counteract the effects of NMDA antagonists like ketamine

However, due to limited human clinical trials, long-term safety is not fully understood