Remarkably, despite having minimal effects on the expression of hepatic markers of inflammation in one of these two studies (86), its administration significantly decreased the gene expression of chemoattractants for different immune cells in the liver of treated mice (interferon -induced protein 10, i.e., CXCL10, and RANTES, i.e., CCL5), which are commonly dysregulated in liver fibrosis (108)
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SLC22A5 mutations impair OCTN2 function, causing primary carnitine deficiency (PCD) (1517), an autosomal recessive disorder characterized by skeletal myopathy, progressive cardiomyopathy, hypoglycemia, and hyperammonemia
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