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Following addition of the -hydroxyl the fatty acid is a substrate for an alcohol dehydrogenase (ADH) which generates an oxo-fatty acid, followed by generation of the corresponding dicarboxylic acid via the action of an aldehyde dehydrogenase (ALDH) family member enzyme
Elssner, T., Preusser, A., Wagner, U
The INHAND Project (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) is a joint initiative of the Societies of Toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP) and North America (STP) to develop an internationally-accepted nomenclature for proliferative and non-proliferative lesions in laboratory animals
Reported reactions include injection-site redness/itch, transient flushing and histamine-type reactions
10.1007/s12020-019-01891-3 93 SmitsM
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