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It stores bile, which breaks down fats to aid with digestion, and then releases it through various ducts

Seek urgent medical advice (contact your GP or NHS 111) if you experience: Severe or persistent abdominal pain, especially if accompanied by vomiting Persistent vomiting or inability to keep fluids down Signs of dehydration (extreme thirst, dark urine, dizziness) Sudden severe upper abdominal pain radiating to the back (possible pancreatitis) Severe right upper abdominal pain (possible gallstones) Severe bloating with vomiting and no passage of stool or gas (possible obstruction) Persistent or severe gastrointestinal symptoms may indicate the need for dose adjustment or, rarely, discontinuation of therapy

Some clinicians suggest that achieving good control of celiac disease symptoms before initiating tirzepatide may improve tolerability, though this approach is based on clinical experience rather than specific studies

Adjusting to a zero carbohydrate diet should be the first intervention before using anything like this

It was approved by the FDA as a prescription medication for people with lipodystrophy