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In the multicenter PIVENS ( PI oglitazone versus V itamin E versus placebo for the treatment of N onalcoholic S teatohepatitis) trial, 247 subjects with MASH but not diabetes mellitus were randomized to receive 30 mg/day of pioglitazone (an insulin-sensitizing drug), 800 IU/day (536 mg/day) of RRR --tocopherol, or a placebo for 96 weeks (97)
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APOE genotype dependent molecular abnormalities in the cerebrovasculature of Alzheimers disease and age-matched non-demented brains
It helps to reduce dark spots, pigmentation and melanin production
Structure-based discovery of opioid analgesics with reduced side effects
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