GIP and GLP-1 may exert long-term effects on -cell survival and proliferation, potentially delaying the development of and even reversing T2DM
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Additionally, ontological terms related to CVD were observed, including hypertension (ACE, ADIPOQ, ADRB2, ALB, CASP3, CAV1, CRH, DPP4, FOS, GHRL, GNB3, INS, IRS1, LEP, LEPR, MGAM, NOS3, NPPA, NPY, POMC, PPARA, PPARG, PTH, REN, SST, VIP), calcium regulation in the cardiac cell (ADCY5-6-8, ADRB2, ARRB1-2, GNAQ, GNAS, GNB1-5, GNG11-13, GNG2-8, GNGT1), and process failing heart cytosolic accumulation of amino acids that can promote the activation of mTOR (AKT1, IRS1, IRS2)