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Altogether, this dataset suggests that prolonged, but not acute, activation of GLP-1R induces metabolic reprogramming leading to increased glycolysis and cellular hypertrophy in BRIN-BD11 cells

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Sallman DA, DeZern AE, Garcia-Manero G, Steensma DP, Roboz GJ, Sekeres MA, et al

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There is no established evidence that semaglutide directly impairs fertility in men or women