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Setting realistic expectations is crucial: weight loss is gradual, with clinical trials showing approximately 15% weight reduction with semaglutide 2.4 mg at 68 weeks and up to 21% with tirzepatide at 72 weeks, though individual responses vary considerably

If more than 5 days have passed, the missed dose should be skipped, and the regular schedule resumed with the next scheduled dose

Constipation and stomach ache were reported more frequently in the active group (10%) compared to the placebo group (3%)

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