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8 , 9 8 , 9 Weight Loss Medications 11 12 Other medications used off label to treat overweight/obesity include topiramate, zonisamide, bupropion, metformin, pramlintide, and the SGLT2 Inhibitors canagliflozin and dapagliflozin

Mechanism of action as a GLP-1 receptor agonist, which helps regulate appetite and food intake

In one mouse model of sepsis-associated encephalopathy, disease onset is initiated by intestinal barrier disruption, which results in sepsis and neurological dysfunction [237]

Avoid fatty, greasy, or heavily spiced meals during your first few weeks on treatment