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10.1126/science.abn8861 Science 5 AraiK.LoE
The LEAD-3 trial assigned patients to randomly receive monotherapies of liraglutide 1.2 mg/day, liraglutide 1.8 mg/day, and glimepiride 8 mg/day (61)
This gives Mounjaro a slight advantage in achieving faster weight-loss results. In a head-to-head clinical trial, Lilly reported that tirzepatide led to an average weight reduction of 20.2%, compared to 13.7% with semaglutide after 72 weeks of treatmenta 47% greater relative weight loss with tirzepatide
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