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The method as claimed in claim 2, wherein the strain activation method in step (2) is: first-level strain activation: inoculating frozen recombinant escherichia coli into an activation culture medium according to the ratio of 1:1000, and carrying out constant-temperature shaking culture at the culture temperature of 37.0 +/-1.0 , the rotation speed of 220 +/-10 rpm for 12-16 h until strain OD 600 Obtaining a first-stage activated seed culture solution when the value is 4.0-8.0

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