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Tirzepatide is a synthetic dual-agonist peptide that acts on both the glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, making it a widely used reference compound in metabolic and receptor-signalling research models
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In vitro transwell assays yielded consistent results: neutralization of CCL5 impaired T cell recruitment, recapitulating the suppressive effect of supernatants from high-folate tumor cells (Fig
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