They required a delivery system that could carry glutathione past the stratum corneum to reach dermal fibroblasts, a feat impossible for standard formulations
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Finally, they reflect pathways likely additional to those involved in the angiogenesis (Vukojevic et al., 2018), recently associated in particular with the increased expression, internalization of VEGFR2, and the activation of the VEGFR2-Akt-eNOS signaling pathway ( Genes Expression as Support ), given the rapid presentation of all of these effects, which occurred before the process of angiogenesis could be initiated (Sikiric et al., 1993
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It could also alleviate the size of myocardial infarction and the subsequent decrease in cardiac function in rats [145]