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The primary antibodies employed were: P53 (Proteintech, 60283-2-Ig), pSer46-P53 (CST, 2521), FOXO4 (Proteintech, 21535-1-AP), P21 (CST, 2947), P16 (CST, 18769), BAX (CST, 2772), BCL2 (CST, 3498), Ki-67 (Proteintech, 84192-4-RR), Lamin B (CST, 13435), Cleaved Caspase 3 (CST, 9664), -H2AX (Abcam, ab81299), and GAPDH (Abcam, ab8245) as an internal reference for normalizing protein expression levels

The peer-reviewed literature is also concentrated within a single research group (Watowich lab, University of Texas at Austin) and its industry partner Ridgeline Therapeutics, with limited independent replication to date

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BPC-157 has been one of those supplements that lived in this weird gray zone for years your gym friends swore by it, people in chronic pain forums talked about it like it was magic, and compounding pharmacies were quietly making it available to anyone with a prescription and a credit card