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While we did not measure downstream signaling responses in -cells after GRK2 knockdown, previous literature describes increased Gs-mediated signaling upon GRK2 depletion or inhibition [58,59,60,61]

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This leads to augmented production of iron-dependent lipid reactive oxygen species (ROS) and induces ferroptosis in tumor cells (7)

Ipamorelin is a more selective GHRP due to its distinct mode of action, which may impact growth hormone patterns linked with its secretion in experimental models

Ozkok, A