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Others are specifically approved for chronic weight loss treatment in people who meet clinical criteria

This is not a true allergic reaction in most cases but rather direct mast cell activation

The AEs in REAC files are encoded by the preferred terms (PTs) in the Medical Dictionary for Regulatory Activities (MedDRA) terminology, which is comprised of 27 system organ classes (SOCs) ( Demographics (gender, age), reporting characteristics (reporting region, year, occupation of reporters), and indications of reports of GLP-1 RA-associated gastrointestinal toxicities were analyzed