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AOD9604 alone significantly improved both gross morphological and histopathological cartilage scores versus saline controls, and the combination of AOD9604 with hyaluronic acid produced superior outcomes to either agent administered alone including significantly shorter lameness periods
Presented for research literature review only Taniguchi N (1988)
0.22 m) immediately prior to use Aliquot and store reconstituted solutions at 20 C (or lower) to minimise degradation Avoid repeated freezethaw cycles Due to reported low intrinsic stability in vitro, prepare fresh working solutions when possible Specifications Summary Precautions & Notes Experimental behaviour of DSIP is dependent on concentration, exposure duration, and model system Buffer composition, pH, and enzymatic activity may influence peptide stability Due to reported rapid degradation in some in vitro systems, appropriate controls are recommended Literature reports describe heterogeneous and sometimes contradictory findings across models Intended strictly for laboratory research use
E., Reyes, A., Nieto-Satelo, J., Feldman, L., and Cassab, G