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zero published human clinical trials as of this writing a 2021 peer-reviewed review states plainly that no NNMT-targeted clinical trials have been reported

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Okabe K, et al

Dimensions: 4367 x 2915 px | 37 x 24.7 cm | 14.6 x 9.7 inches | 300dpi Date taken: 26 January 2021 Location: Essex, UK More information: Hydroxocobalamin, also known as vitamin B12a and hydroxycobalamin, is a vitamin found in food and used as a dietary supplement

Reusing them increases the risk of infection and contamination