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Key Developments March 2026: Structure Therapeutics reported positive Phase II ACCESS II results for aleniglipron, its once-daily oral small-molecule GLP-1 receptor agonist, showing placebo-adjusted mean weight loss of up to 16.3% at 44 weeks in obesity patients
2009 Aug 10;6:31
Weight Loss Maintenance Trial Findings The trial assigned 205 tirzepatide recipients (cohort 1) and 171 semaglutide recipients (cohort 2) from SURMOUNT-5 to receive orforglipron or placebo
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Hormonal imbalances can make it much harder to lose weight, especially around the belly
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