BMJ 25(385):e078242 Pokharel Y, Khariton Y, Tang Y, Nassif ME, Chan PS, Arnold SV et al (2017) Association of serial Kansas City Cardiomyopathy Questionnaire assessments with death and hospitalization in patients with heart failure with preserved and reduced ejection fraction: a secondary analysis of 2 randomized clinical trials

What to track Symptoms log: Hot flash frequency and severity Sleep quality (hours, quality 1-10) Energy levels daily Mood and anxiety Brain fog incidents Period timing (if still menstruating) Body composition: Weight weekly (understanding fluctuations normal) Body measurements (waist, hips) Photos every 2-4 weeks How clothes fit Muscle vs fat changes Hormone-related: Menstrual cycle length and flow PMS symptoms Breast tenderness Libido changes Vaginal dryness Quality of life: Exercise performance Work productivity Relationship satisfaction Social engagement Overall well-being Bloodwork for perimenopause peptides Baseline testing: Estradiol (estrogen) Progesterone Testosterone (total and free) FSH (follicle-stimulating hormone - elevated in perimenopause) Thyroid panel (TSH, Free T3, Free T4) IGF-1 (growth hormone marker) Fasting glucose and insulin Lipid panel Follow-up (every 3-6 months): IGF-1 (should increase with GH peptides) Thyroid panel Fasting glucose Hormones if on HRT Adjusting based on results: Low IGF-1 still

Variations beyond two days should be discussed with your prescriber to avoid unintended gaps in therapy or dose stacking
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