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There's pressure out there from people who aren't overweight, and I don't know if other clinicians are prescribing it, but that's an issue

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In mouse models, ethanol-induced intestinal dysbiosis and reduced levels of associated metabolites lead to decreased intestinal IL-22 expression [152]

The FDA also explains that the drugs could cause weight loss, and that "weight loss offers no benefit to a pregnant patient and may cause fetal harm." The FDA recommends that people discontinue the medications at least two months before they plan to become pregnant

Hormonal acne is common in teenagers, women with polycystic ovary syndrome (PCOS), and women experiencing hormonal fluctuations during pregnancy or menopause