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2016;129(8):879.e16

In a 12-week trial involving individuals with a BMI of 2743 kg/m, the highest-dose group achieved an 11.3% average weight reduction, a top-tier result for early-stage trials

It partially binds to the opioid receptors without creating the euphoria that opioid induces

In comparison, the proportion of CD8 + reached the initial level within 24 h pi , remained there until 72 h pi , and reached a significantly lower level compared to the baseline at 7 d pi , which was maintained until the end of the trial

Additional research will need to delineate dosing, timing, and safety prior to general use in fertility care