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And to be fair, these types of drugs have been in the making since the early 2000s, according to a 2025 article in Pharmacological Research

The effects of delayed gastric emptying may further compound the risk factors harbored by the obese, diabetic patient: Gastroparesis secondary to diabetes-related autonomic dysfunction Bowel dysmotility from opioids (chronic pain) and prolonged bed-rest Altered oesophageal-gastric anatomy from bariatric surgery Gastric insufflation from overzealous bag-valve ventilation with high PEEP and difficult airway Reduced efficacy of routine antiemetic regime Nausea and vomiting are reported by approximately 50% of patients using GLP-1 agonists, as direct results of reduced gastric motility and activation of central satiety centers

Anti-Inflammatory Benefits Chronic low-grade inflammation, often called "inflammaging," accelerates muscle loss and increases disease risk in older women