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Most of the time high GPX4 expression correlated with a poor prognosis
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Key Clinical Significance Succinylcholine-induced hyperkalemia is most dangerous in patients with: Major burns Neuromuscular disorders (e.g., Duchenne or Becker muscular dystrophy) Severe trauma with muscle injury Prolonged immobilization Significant denervation injuries Because of the risk of fatal cardiac arrhythmias, succinylcholine should be avoided in these high-risk populations , and alternative neuromuscular blocking agents such as rocuronium are often preferred (Hovgaard & Juhl-Olsen, 2021
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You can browse this work through these animal-model studies on PubMed
