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Studies revealed that chronic alcohol consumption inhibited the expression of tet methylcytosine dioxygenase (TET) proteins, resulting in the diminished production of 5-hydroxymethylcytosine, an emerging epigenetic modification
Tumor progression into soft tissues, lymph nodes or distant metastatic sites have been shown to dramatically reduce 5-year overall survival in patients with PTC, highlighting the need for a novel therapeutic approach for highly aggressive forms of PTC 6
(PubMed) Reeves MA, Hoffmann PR
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