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However, surveillance mechanisms that detect and resolve unprogrammed R-loops at repetitive elements remain poorly defined
For weight management, the FDA-approved options are Wegovy (semaglutide), Zepbound (tirzepatide), and Foundayo (orforglipron)
Muscle preservation, bone density maintenance, cardiovascular adaptation, and metabolic health all require attention during aggressive weight loss
Jang, G
Nat Rev Endocrinol 8 , 728742 (2012)
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