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Bremelanotide can cause significant nausea (reported in up to 40% of users in clinical trials), increased blood pressure, and flushing
It should be noted that this population has a higher incidence of stomach carcinoma
What would be most valuable, from a research design perspective, is a pharmacokinetic characterization study in healthy dogs, followed by a controlled model of NSAID-induced gastric mucosal injury, which is both clinically relevant and methodologically well-established in veterinary research
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MedRxiv The Preprint Server for Health Services
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