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6 A high quality mattress, non-toxic sheets, pillowcases and other linens that are made of natural and chemical free materials are also good choices that can provide soothing comfort and a dust-free, allergen-free, fungus-, microbe-, bacteria-, and toxin-free sleeping environment

In both rats induced with IC/PBS and human patients suffering from IC/PBS, there is a notably high expression of these purinergic and muscarinic receptors (Nasrin et al., 2013)

Ait Tayeb AEK, Poinsignon V, Chappell K, Bouligand J, Becquemont L, Verstuyft C

This ensures: Correct dosage Safe administration Personalized treatment plan 2

All authors critically reviewed the manuscript, enriched, developed the main parts, and contributed during the preparation of the tables and figures before submission