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By removing the psychological and practical barriers associated with injectable treatments, oral GLP-1s have the potential to reposition obesity care as a routine, chronic intervention rather than a specialist-led, escalation therapy

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They concluded that the net price of Zepbound would have to come down by 31% and the net price of Wegovy would have to come down by 82% for these drugs to be cost-effective at $100,000 per QALY