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Right now, clinicians are mostly relying on individual symptom monitoring and careful dose adjustments

Waist circumference was measured at screening, weeks 1 and 6 and EoT

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The leading theory in our field is that in those patients who have dramatic responses to the GLP-1 agonists those who suddenly lose a lot of weight or have a sudden crash of A1c the rapidity of change may precipitate the worsening of diabetic retinopathy

If things are still wonky (missed periods, short cycles, irregular patterns) after three months, its time to loop in a fertility expert