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References Svensson J et al., J Endocrinol Invest, 1998 21(9):692-699
30 (Pt 6), 10641070 (2002)
The clinical success of exenatide is based on its ability to effectively mimic incretin effects, its resistance to DPP-4, and its longer duration of action compared to native human GLP-1
(c) nuclear translocation of predominantly p65/p50 dimers to induce transcription of target genes, including well-established FLICE-like inhibitory protein (c-FLIP) and apoptosis protein inhibitors (c-IAP)
Ipamorelin is a peptide made of five amino acids
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