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Structurally, tirzepatide is engineered to mimic the primary amino acid sequence of GIP while retaining partial agonistic activity at the GLP-1 receptor
In this manuscript, we discuss GLP-1 based antiobesity medication focusing on its mechanism, clinical trial results, and potential adverse events
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For example, caffeine and alcohol have been shown to reduce its effectiveness
GLP-1 medications can cause profound appetite suppression an effect that, for someone with restrictive eating, can reinforce dangerous patterns of food restriction, reduce food intake to medically dangerous levels, and provide what feels like medical sanction for not eating
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