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Safe GLP-1 programs usually require labs before starting treatment and then repeat them after 36 months to confirm safety and adjust care as needed

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Injectable peptides (like BPC 157 or GHS) are often sold as research chemicals, meaning they arent officially approved for human use

While this study did not include metformin as background therapy, it established tirzepatide's independent weight loss efficacy (up to 22.5% body weight reduction with the 15 mg dose at 72 weeks)