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If there is no real check on compounded drugs, doses can be wrong, there can be unwanted stuff in them, or they may be made where it's not clean
GLP-1 medications solve this by using modified versions of the hormone that resist enzymatic breakdown, maintaining elevated levels for days or even a full week depending on the formulation
From a practical standpoint, some patients find it helpful to administer Ozempic in the evening, particularly during the initial titration phase when gastrointestinal side effects may be more pronounced
Sci Transl Med 5:209ra151 Finan B, Yang B, Ottaway N et al (2015) A rationally designed monomeric peptide triagonist corrects obesity and diabetes in rodents
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