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Specific metabolite subclasses were associated with asthma diagnosis (e.g., sphingosines, sphinganines, serotonin, indole-3-propionate), FEV 1 (e.g., ceramides, sphingomyelins, kynurenine), FVC (e.g., sphingomyelins, quinolinate), and asthma exacerbations (e.g., ceramides, methylobutyrate, isobutyrate)

They also support liver health, which is essential for effectively metabolizing fats

In summary, the potential impact of long-acting GLP-1 RAs on human thyroid C cells needs further study

In those cases, the data may still be scientifically useful, but it should not be described as exclusively NNMT-mediated without additional evidence

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