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While this class of drugs was initially approved for type 2 diabetes, it has recently gained global attention for cardiovascular risk reduction and weight loss in patients with obesity, irrespective of the presence of diabetes
doi: 10.1152/ajpendo.1985.249.6.E603 177 HaunerHGlattingGKaminskaDPfeifferEF
facilitating over-stimulated or sustained inflammatory responses with interferon and cytokine release, influencing ROS production, iron storage, platelet coagulability, cytokine production stimulation, regulation of fission and fusion, mitochondrial biogenesis, and interference of apoptosis and mitophagy (312319)
Despite a recommended daily intake as low as 6 micrograms, B12 deficiency remains common, particularly among individuals following vegan or vegetarian diets
Interactions with hydroxymethylglutaryl-coenzyme A reductase inhibitors
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