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Unlike Ozempic, which works through GLP-1 alone, retatrutide adds GIP and glucagon receptor activity on top of the GLP-1 backbone
The GLP-1 receptor belongs to class B of the G-protein-coupled receptors, a subfamily characterized by a large N-terminal extracellular ligand binding domain
If you want to dive into the research, check it out here
Available at: Buonanno S, Gaggiano C, Terribili R, Cantarini L, Frediani B, Gentileschi S
It belongs to a broader category of GLP-1 receptor agonists, and understanding how it compares to alternatives helps researchers make informed decisions about which compound best serves their specific research objectives
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